PFAS RegulationsState, federal and global register

Is This Chemical a PFAS?

Type a chemical name, CAS number or SMILES string. The checker reads the structure and tests it against the three PFAS definitions the laws use: the fully fluorinated carbon wording of Maine, Minnesota and most states, the OECD wording of the EU, and the structural test in the federal TSCA reporting rule. Of the 322 entries in the built-in table, 187 are a PFAS under one definition and not another.

How the three tests work

Fully fluorinated carbon. A class of fluorinated organic chemicals containing at least one fully fluorinated carbon atom. Washington wrote this sentence into its 2018 food packaging law, and most states have used it since. Maine's PFAS rule and a federal statute (15 U.S.C. 8931) define a fully fluorinated carbon atom as one on which all the hydrogen substituents have been replaced by fluorine, and Minnesota's Department of Agriculture applies that test to pesticides. Read that way, CF3 and CF2 groups qualify and so does a single fluorine on an aromatic ring. The checker uses that reading.

OECD CF3 or CF2. Any substance that contains at least one fully fluorinated methyl (CF3) or methylene (CF2) carbon atom without any H, Cl, Br or I attached to it. The EU, Denmark and New Zealand use it. It needs a saturated carbon carrying at least two fluorines, so a lone fluorine on a ring, a CHF2 group or a carbon carrying chlorine beside its fluorines falls outside it.

TSCA structures. EPA's reporting rule (40 CFR 705.3) counts a substance as PFAS if it contains one of three saturated substructures: R-CF2-CF(R')R'', with any R groups; R-CF2-O-CF2-R', where R and R' are fluorine, oxygen or saturated carbon; or CF3-C(CF3)R'R'', where R' and R'' are fluorine or saturated carbon. Single fluorinated carbons, fluorinated aromatic rings and olefins are outside it. New Hampshire's product law adopts this definition by reference.

A yes means the structure contains what the definition describes. It does not mean a law restricts the chemical: each law also limits itself to products, to intentionally added PFAS, and to its own exemptions and named lists. West Virginia's foam law needs two fully fluorinated carbons and excludes polymers, so it gets its own row. Fluoropolymers are tested on a representative repeating unit, refrigerant blends count if any component does, and salts are tested one ion at a time. A one-carbon compound with a double bond, such as carbonyl fluoride, is marked as depending on whether it counts as organic.

Names that are not in the built-in table go from your browser to PubChem, the National Library of Medicine's chemical database, which returns the structure; the tests then run in your browser. The page address includes the name you looked up, and the site's analytics record page addresses if you allow them. See the privacy policy.

The built-in table

322 entries, with structures from PubChem as of October 29, 2026. 94 are PFAS under all three tests. Open a group and pick a name for the reasons.

Legacy and long-chain PFAS 17
ChemicalFully fluorinated carbonStatesOECD CF3 or CF2OECDTSCA structuresTSCA
C8H4F15NO2, CAS 3825-26-1YesYesYes
C12H10F17NO3S, CAS 1691-99-2YesYesYes
C10H6F17NO2S, CAS 4151-50-2YesYesYes
C9H4F17NO2S, CAS 31506-32-8YesYesYes
C10HF21O3S, CAS 335-77-3YesYesYes
C10HF19O2, CAS 335-76-2YesYesYes
C12HF23O2, CAS 307-55-1YesYesYes
C7HF13O2, CAS 375-85-9YesYesYes
C6HF13O3S, CAS 355-46-4YesYesYes
C9HF17O2, CAS 375-95-1YesYesYes
C8H2F17NO2S, CAS 754-91-6YesYesYes
C8HF17O3S, CAS 1763-23-1YesYesYes
C8HF15O2, CAS 335-67-1YesYesYes
C8F16O, CAS 335-66-0YesYesYes
C14HF27O2, CAS 376-06-7YesYesYes
C11HF21O2, CAS 2058-94-8YesYesYes
C8F17KO3S, CAS 2795-39-3YesYesYes
Short-chain and replacement PFAS 18
ChemicalFully fluorinated carbonStatesOECD CF3 or CF2OECDTSCA structuresTSCA
C7H2F12O4, CAS 919005-14-4YesYesYes
C6H4F11NO3, CAS 62037-80-3YesYesYes
C6HF11O3, CAS 13252-13-6YesYesYes
C4H2F9NO2S, CAS 30334-69-1YesYesYes
C4HF9O4S, CAS 113507-82-7YesYesYes
C3HF5O3, CAS 674-13-5YesYesNo
C5HF9O4, CAS 151772-58-6YesYesYes
C4F10O2S, CAS 375-72-4YesYesYes
C4HF9O3S, CAS 375-73-5YesYesYes
C4HF7O2, CAS 375-22-4YesYesYes
C7HF15O3S, CAS 375-92-8YesYesYes
C6HF11O2, CAS 307-24-4YesYesYes
C5HF11O3S, CAS 2706-91-4YesYesYes
C5HF9O2, CAS 2706-90-3YesYesYes
C3HF5O2, CAS 422-64-0YesYesYes
C2HF3O2, CAS 76-05-1YesYesNo
CH2F3NO2S, CAS 421-85-2YesYesNo
CHF3O3S, CAS 1493-13-6YesYesNo
Fluorotelomers 13
ChemicalFully fluorinated carbonStatesOECD CF3 or CF2OECDTSCA structuresTSCA
C12H5F21O, CAS 865-86-1YesYesYes
C8H4F13I, CAS 2043-57-4YesYesYes
C6H5F9O, CAS 2043-47-2YesYesYes
C8H5F11O2, CAS 914637-49-3YesYesYes
C11H7F13O2, CAS 17527-29-6YesYesYes
C8H5F13O, CAS 647-42-7YesYesYes
C16H9F26O4P, CAS 57677-95-9YesYesYes
C15H20F13N2O4S+, CAS 2102096-95-5YesYesYes
C8H5F13O3S, CAS 27619-97-2YesYesYes
C10H5F17O, CAS 678-39-7YesYesYes
C14H9F17O2, CAS 1996-88-9YesYesYes
C10H5F17O3S, CAS 39108-34-4YesYesYes
C8H3F13, CAS 25291-17-2YesYesYes
Fluoropolymers 11
ChemicalFully fluorinated carbonStatesOECD CF3 or CF2OECDTSCA structuresTSCA
(C2H4)n(C2F4)m, CAS 25038-71-5YesYesYes
(C2F4)n(C3F6)m, CAS 25067-11-2YesYesYes
C11H5F19, CAS 9011-17-0YesYesYes
C10HF21O5S, CAS 31175-20-9YesYesYes
(C2F4)n(C5F10O)m, CAS 26655-00-5YesYesYes
(C3F6O)n, CAS 60164-51-4YesYesYes
(C2ClF3)n, CAS 9002-83-9YesYesYes
(C2F4)n, CAS 9002-84-0YesYesYes
(C2H3F)n, CAS 24981-14-4NoNoNo
(C2H2F2)n, CAS 24937-79-9YesYesNo
C24H20F26O4YesYesYes
Refrigerants, propellants and fluorinated gases 47
ChemicalFully fluorinated carbonStatesOECD CF3 or CF2OECDTSCA structuresTSCA
C3HF7, CAS 431-89-0YesYesYes
C3H2F6, CAS 431-63-0YesYesYes
C2HClF4, CAS 2837-89-0YesYesYes
C2H2F4, CAS 811-97-2YesYesYes
C3H2F6, CAS 690-39-1YesYesNo
C4H5F5, CAS 406-58-6YesYesNo
C3H3F5, CAS 460-73-1YesYesNo
C2H3F3, CAS 420-46-2YesYesNo
C2H2F4, CAS 359-35-3NoNoYes
C2H4F2, CAS 75-37-6NoNoNo
C3H2ClF3, CAS 2730-43-0YesYesNo
C3H2F4, CAS 754-12-1YesYesNo
C3H3ClF4, CAS 421-73-8YesYesYes
CBrClF2, CAS 353-59-3DependsNoNo
CBrF3, CAS 75-63-8DependsNoNo
CHClF2, CAS 75-45-6NoNoNo
C2ClF3, CAS 79-38-9YesNoNo
C4H2F6, CAS 692-49-9YesYesNo
CCl2F2, CAS 75-71-8DependsNoNo
CH2F2, CAS 75-10-5NoNoNo
C2H5F, CAS 353-36-6NoNoNo
CHF3, CAS 75-46-7NoNoNo
C2F6, CAS 76-16-4YesYesYes
C3F6, CAS 116-15-4YesYesNo
F3N, CAS 7783-54-2NoNoNo
C3F8, CAS 76-19-7YesYesYes
C2HF5, CAS 354-33-6YesYesYes
C6F12O, CAS 756-13-8YesYesYes
C4F8, CAS 115-25-3YesYesYes
Blend of R-125, R-143a and R-134aYesYesYes
Blend of R-32, R-125 and R-134aYesYesYes
Blend of R-32 and R-125YesYesYes
Blend of R-32, R-125, R-1234yf, R-134a and R-1234zeYesYesYes
Blend of R-32, R-125, R-1234yf and R-134aYesYesYes
Blend of R-32, R-125 and R-1234yfYesYesYes
Blend of R-32 and R-1234yfYesYesNo
Blend of R-32 and R-1234yfYesYesNo
Blend of R-125 and R-143aYesYesYes
Blend of R-1234yf and R-134aYesYesYes
F6S, CAS 2551-62-4NoNoNo
C2F4, CAS 116-14-3YesNoNo
CF4, CAS 75-73-0YesYesNo
C3H2F4, CAS 29118-24-9YesYesNo
CCl3F, CAS 75-69-4DependsNoNo
C2HF3, CAS 359-11-5YesNoNo
C2H3F, CAS 75-02-5NoNoNo
C2H2F2, CAS 75-38-7YesNoNo
Anesthetics 6
ChemicalFully fluorinated carbonStatesOECD CF3 or CF2OECDTSCA structuresTSCA
C3H2F6O, CAS 57041-67-5YesYesYes
C3H2ClF5O, CAS 13838-16-9YesYesYes
C2HBrClF3, CAS 151-67-7YesYesNo
C3H2ClF5O, CAS 26675-46-7YesYesNo
C3H4Cl2F2O, CAS 76-38-0YesYesNo
C4H3F7O, CAS 28523-86-6YesYesNo
Pharmaceuticals 69
ChemicalFully fluorinated carbonStatesOECD CF3 or CF2OECDTSCA structuresTSCA
C19H22F3N5O2S, CAS 1217486-61-7YesYesNo
C21H15F4N5O2S, CAS 956104-40-8YesYesNo
C23H21F7N4O3, CAS 170729-80-3YesYesNo
C23H27Cl2N3O2, CAS 129722-12-9NoNoNo
C33H35FN2O5, CAS 134523-00-5YesNoNo
C22H29FO5, CAS 378-44-9YesNoNo
C18H14F4N2O4S, CAS 90357-06-5YesYesNo
C17H14F3N3O2S, CAS 169590-42-5YesYesNo
C22H22F3N, CAS 226256-56-0YesYesNo
C17H18FN3O3, CAS 85721-33-1YesNoNo
C22H29FO5, CAS 50-02-2YesNoNo
C13H8F2O3, CAS 22494-42-4YesNoNo
C27H30F6N2O2, CAS 164656-23-9YesYesNo
C14H9ClF3NO2, CAS 154598-52-4YesYesNo
C26H34F3N7O4S, CAS 2216712-66-0YesYesNo
C8H10FN3O3S, CAS 143491-57-0YesNoNo
C21H16F4N4O2S, CAS 915087-33-1YesYesNo
C20H21FN2O, CAS 128196-01-0YesNoNo
C24H21F2NO3, CAS 163222-33-1YesNoNo
C17H20F6N2O3, CAS 54143-55-4YesYesNo
C20H25FN2O3, CAS 956103-76-7NoNoNo
C13H12F2N6O, CAS 86386-73-4YesNoNo
C6H11FO5, CAS 63503-12-8NoNoNo
C21H29FO5, CAS 127-31-1YesNoNo
C16H12FN3O3, CAS 1622-62-4YesNoNo
C14H11F3N2O2, CAS 38677-85-9YesYesNo
C24H30F2O6, CAS 67-73-2YesNoNo
C22H29FO4, CAS 426-13-1YesNoNo
C4H3FN2O2, CAS 51-21-8YesNoNo
C17H18F3NO, CAS 54910-89-3YesYesNo
C20H29FO3, CAS 76-43-7YesNoNo
C22H26F3N3OS, CAS 69-23-8YesYesNo
C15H13FO2, CAS 5104-49-4YesNoNo
C11H11F3N2O3, CAS 13311-84-7YesYesNo
C14H11FN2OS, CAS 765922-62-1YesNoNo
C25H31F3O5S, CAS 80474-14-2YesNoNo
C24H26FNO4, CAS 93957-54-1YesNoNo
C15H21F3N2O2, CAS 54739-18-3YesYesNo
C9H11F2N3O4, CAS 95058-81-4YesYesNo
C21H23ClFNO2, CAS 52-86-8YesNoNo
C24H28N2O3, CAS 873054-44-5NoNoNo
C16H14F3N3O2S, CAS 103577-45-3YesYesNo
C12H9F3N2O2, CAS 75706-12-6YesYesNo
C39H32ClF10N7O5S2, CAS 2189684-44-2YesYesNo
C29H28F4N4O4, CAS 917389-32-3YesYesNo
C18H20FN3O4, CAS 100986-85-4YesNoNo
C16H20FN3O4, CAS 165800-03-3YesNoNo
C24H18F2N2O5, CAS 936727-05-8YesYesNo
C17H16F6N2O, CAS 53230-10-7YesYesNo
C18H13ClFN3, CAS 59467-70-8YesNoNo
C28H22F3N7O, CAS 641571-10-0YesYesNo
C19H20FNO3, CAS 61869-08-7YesNoNo
C25H24FNO4, CAS 147511-69-1YesNoNo
C21H15ClF4N4O3, CAS 755037-03-7YesYesNo
C8H5F3N2OS, CAS 1744-22-5YesYesNo
C23H27FN4O2, CAS 106266-06-2YesNoNo
C22H28FN3O6S, CAS 287714-41-4YesNoNo
C29H35F3N2O3, CAS 1230487-00-9YesYesNo
C16H15F6N5O, CAS 486460-32-6YesYesNo
C22H29FN3O9P, CAS 1190307-88-0YesNoNo
C21H16ClF3N4O3, CAS 284461-73-0YesYesNo
C25H34F2O5, CAS 209860-87-7YesYesNo
C19H15F3N2O3, CAS 869572-92-9YesYesNo
C12H9F3N2O2, CAS 163451-81-8YesYesNo
C26H27F3N2O6, CAS 1152311-62-0YesYesNo
C21H27FO6, CAS 124-94-7YesNoNo
C21H24F3N3S, CAS 117-89-5YesYesNo
C29H26F3N5O3, CAS 1374248-77-7YesYesNo
C16H14F3N5O, CAS 137234-62-9YesNoNo
Pesticides and veterinary drugs 89
ChemicalFully fluorinated carbonStatesOECD CF3 or CF2OECDTSCA structuresTSCA
C14H7ClF3NO5, CAS 50594-66-6YesYesNo
C26H17ClF9N3O3, CAS 1093861-60-9YesYesNo
C13H16F3N3O4, CAS 1861-40-1YesYesNo
C23H22ClF3O2, CAS 82657-04-3YesYesNo
C18H12Cl2F3N3O, CAS 581809-46-3YesNoNo
C25H14BrF11N2O2, CAS 1207727-04-5YesYesYes
C18H14BrCl2N5O2, CAS 500008-45-7NoNoNo
C15H11BrClF3N2O, CAS 122453-73-0YesYesNo
C19H14BrClN6O2, CAS 736994-63-1NoNoNo
C24H24F3NO4, CAS 400882-07-7YesYesNo
C19H12Cl3N3O2S, CAS 1263629-39-5NoNoNo
C14H9ClF2N2O2, CAS 35367-38-5YesNoNo
C19H11F5N2O2, CAS 83164-33-4YesYesNo
C15H16F5NO2S2, CAS 97886-45-8YesYesNo
C13H14F3N3O4, CAS 55283-68-6YesYesNo
C12H4Cl2F6N4OS, CAS 120068-37-3YesYesNo
C9H6F3N3O, CAS 158062-67-0YesYesNo
C12H8F3N5O3S, CAS 145701-23-1YesNoNo
C20H21F3N2O5, CAS 229977-93-9YesYesNo
C19H20F3NO4, CAS 79241-46-6YesYesNo
C13H4Cl2F6N4O4, CAS 79622-59-6YesYesNo
C23H22F7IN2O4S, CAS 272451-65-7YesYesYes
C12H10F3N4NaO6S, CAS 181274-17-9YesYesNo
C26H23F2NO4, CAS 70124-77-5NoNoNo
C12H6F2N2O2, CAS 131341-86-1YesYesNo
C7H5ClF3NO2S2, CAS 318290-98-1YesNoNo
C14H13F4N3O2S, CAS 142459-58-3YesYesNo
C21H11ClF6N2O3, CAS 101463-69-8YesYesNo
C19H16ClF3O4, CAS 918162-02-4YesYesNo
C18H20F3N3O, CAS 1383809-87-7YesNoNo
C28H22Cl2FNO3, CAS 69770-45-2YesNoNo
C16H12ClF4N3O4, CAS 62924-70-3YesYesNo
C19H15FN2O4, CAS 103361-09-7YesNoNo
C10H11F3N2O, CAS 2164-17-2YesYesNo
C16H11ClF6N2O, CAS 658066-35-4YesYesNo
C2H4FNO, CAS 640-19-7NoNoNo
C12H10Cl2F3NO, CAS 61213-25-0YesYesNo
C21H16ClFN4O5, CAS 361377-29-9YesNoNo
C12H11ClF2N2O2, CAS 951659-40-8NoNoNo
C15H13F3N5NaO7S, CAS 144740-54-5YesYesNo
C16H8Cl2FN5O, CAS 136426-54-5YesNoNo
C22H17Cl2F6N3O3, CAS 864731-61-3YesYesNo
C7H5Cl2FN2O3, CAS 69377-81-7YesNoNo
C18H14F3NO2, CAS 96525-23-4YesYesNo
C16H15F2N3Si, CAS 85509-19-9YesNoNo
C17H16F3NO2, CAS 66332-96-5YesYesNo
C16H13F2N3O, CAS 76674-21-0YesNoNo
C26H22ClF3N2O3, CAS 69409-94-5YesYesNo
C18H12F5N3O, CAS 907204-31-3YesNoNo
C15H10ClF3N2O6S, CAS 72178-02-0YesYesNo
C16H13ClF3NO4, CAS 72619-32-0YesYesNo
C16H8Cl2F6N2O3, CAS 86479-06-3YesYesYes
C22H17ClF3N3O7, CAS 173584-44-6YesYesNo
C18H21F2N3O, CAS 1352994-67-2NoNoNo
C19H21ClF3N3O, CAS 1255734-28-1YesNoNo
C15H12F3NO4S, CAS 141112-29-0YesYesNo
C19H15ClF3NO7, CAS 77501-63-4YesYesNo
C23H19ClF3NO3, CAS 91465-08-6YesYesNo
C17H8Cl2F8N2O3, CAS 103055-07-8YesYesYes
C14H13NO7S, CAS 104206-82-8NoNoNo
C12H9ClF3N3O, CAS 27314-13-2YesYesNo
C17H9ClF8N2O4, CAS 116714-46-6YesYesYes
C17H7Cl2F9N2O3, CAS 121451-02-3YesYesYes
C15H11ClF3NO4, CAS 42874-03-3YesYesNo
C16H14F5N5O5S, CAS 219714-96-2YesYesNo
C18H16F3NO4, CAS 117428-22-5YesYesNo
C15H12F4N4O7S, CAS 86209-51-0NoNoNo
C13H17F3N4O4, CAS 29091-21-2YesYesNo
C16H16Cl3F2N3O2, CAS 1228284-64-7NoNoNo
C22H23ClF2N4O2, CAS 1803108-03-3NoNoNo
C12H14F5N3O4S, CAS 447399-55-5YesYesNo
C17H17ClF4N4O5S, CAS 372137-35-4YesYesNo
C23H18Cl2F4N2O5S, CAS 1398609-39-6YesYesNo
C2H2FNaO2, CAS 62-74-8NoNoNo
C10H10F3N3OS, CAS 946578-00-3YesYesNo
C26H22ClF3N2O3, CAS 102851-06-9YesYesNo
C14H6Cl2F4N2O2, CAS 83121-18-0YesNoNo
C17H14ClF7O2, CAS 79538-32-2YesYesNo
C17H16ClF3O6S, CAS 335104-84-2YesYesNo
C13H11Cl2F4N3O, CAS 112281-77-3YesYesYes
C16H17F5N2O2S, CAS 117718-60-2YesYesNo
C21H22ClN3O2, CAS 129558-76-5NoNoNo
C15H12Cl2F4O2, CAS 118712-89-3YesNoNo
C20H19F3N2O4, CAS 141517-21-7YesYesNo
C15H15ClF3N3O, CAS 68694-11-1YesYesNo
C15H10ClF3N2O3, CAS 64628-44-0YesYesNo
C13H16F3N3O4, CAS 1582-09-8YesYesNo
C17H19F3N6O6S, CAS 126535-15-7YesYesNo
C16H18ClF3N4OS, CAS 1477919-27-9YesYesNo
Solvents, intermediates and industrial chemicals 37
ChemicalFully fluorinated carbonStatesOECD CF3 or CF2OECDTSCA structuresTSCA
C8H11F6N3O4S2, CAS 174899-82-2YesYesNo
C16H19F17O3Si, CAS 101947-16-4YesYesYes
C2H3F3O, CAS 75-89-8YesYesNo
C6H5F2N, CAS 367-25-9YesNoNo
C8H5F3O2, CAS 433-97-6YesYesNo
C13H8F2O, CAS 345-92-6YesNoNo
C7H4ClF3, CAS 98-56-6YesYesNo
C6H5FO, CAS 371-41-5YesNoNo
C7H7F, CAS 352-32-9YesNoNo
C7H5F3, CAS 98-08-8YesYesNo
C2HF6NO4S2, CAS 82113-65-3YesYesNo
CF2O, CAS 353-50-4DependsNoNo
C6H5F9O, CAS 631897-30-8YesYesYes
C6H5F, CAS 462-06-6YesNoNo
C4F6, CAS 685-63-2YesNoNo
C3F6O, CAS 684-16-2YesYesNo
C6F6, CAS 392-56-3YesNoNo
C3H2F6O, CAS 920-66-1YesYesNo
C2HF6LiNO4S2, CAS 90076-65-6YesYesNo
C5H3F9O, CAS 163702-07-6YesYesYes
C3H3F3O2, CAS 431-47-0YesYesNo
C5F8, CAS 559-40-0YesYesYes
C6HF5O, CAS 771-61-9YesNoNo
C7F14, CAS 355-02-2YesYesYes
C5F10O, CAS 1623-05-8YesYesYes
C10F18, CAS 306-94-5YesYesYes
C8F16, CAS 335-27-3YesYesYes
C6F14, CAS 355-42-0YesYesYes
C4F8, CAS 382-21-8YesYesNo
C8F18, CAS 307-34-6YesYesYes
C8BrF17, CAS 423-55-2YesYesYes
C14H15F17O3Si, CAS 96305-13-4YesYesYes
C12F27N, CAS 311-89-7YesYesYes
C9F21N, CAS 338-83-0YesYesYes
C4F6O3, CAS 407-25-0YesYesNo
CHF3O, CAS 1493-11-4YesYesNo
C3F6O, CAS 1187-93-5YesYesNo
Fluoride salts and non-PFAS comparisons 15
ChemicalFully fluorinated carbonStatesOECD CF3 or CF2OECDTSCA structuresTSCA
BF3, CAS 7637-07-2NoNoNo
CaF2, CAS 7789-75-5NoNoNo
C13H10, CAS 86-73-7NoNoNo
C20H12O5, CAS 2321-07-5NoNoNo
F2, CAS 7782-41-4NoNoNo
Ca5FO12P3, CAS 1306-05-4NoNoNo
F6H2Si, CAS 16961-83-4NoNoNo
FH, CAS 7664-39-3NoNoNo
F6LiP, CAS 21324-40-3NoNoNo
(C2H4)n, CAS 9002-88-4NoNoNo
F2HK, CAS 7789-29-9NoNoNo
FNa, CAS 7681-49-4NoNoNo
FNa2O3P, CAS 10163-15-2NoNoNo
F2Sn, CAS 7783-47-3NoNoNo
C16H36FN, CAS 429-41-4NoNoNo

The tests are the register's reading of each definition applied to a structure. Agencies may read a definition differently, and the cited law controls. Not legal advice.

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